IMPURITIES AVAILABLE FOR 'Ruboxistaurin'

Omsynth Lifesciences Pvt. Ltd. is one of the leading manufacturer and exporter of Ruboxistaurin. Ruboxistaurin is an orally administered selective inhibitor of protein kinase C-β (PKC-β), an enzyme implicated in diabetic microvascular complications. By blocking PKC-β activation, it reduces abnormal vascular permeability, inflammation, and neovascular changes associated with chronic hyperglycemia. The drug was primarily investigated for diabetic retinopathy, aiming to slow progression of vision-threatening changes. Clinical studies showed potential benefits in reducing moderate vision loss, though results were variable. Despite promising mechanisms, ruboxistaurin did not achieve regulatory approval due to insufficient efficacy in pivotal trials. It is generally well tolerated, with mild gastrointestinal or headache-related adverse effects reported. The compound has a long half-life and favorable oral bioavailability. Research interest continues in exploring PKC-β inhibition for other vascular or inflammatory conditions. Buy high quality Ruboxistaurin from Omsynth Lifesciences.