IMPURITIES AVAILABLE FOR 'Riociguat'

Omsynth Lifesciences Pvt. Ltd. is one of the leading manufacturer and exporter of Riociguat. Riociguat is a soluble guanylate cyclase (sGC) stimulator used to treat pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). It works by directly stimulating sGC and enhancing the nitric oxide (NO) signaling pathway, leading to increased cyclic guanosine monophosphate (cGMP) levels, vasodilation, and improved blood flow in the pulmonary arteries. This reduces pulmonary vascular resistance and improves exercise capacity and quality of life. Riociguat is administered orally and has a favorable pharmacokinetic profile with predictable absorption. Common side effects include headache, dizziness, hypotension, dyspepsia, and peripheral edema. It is contraindicated in pregnancy and when used with nitrates or PDE5 inhibitors due to the risk of severe hypotension. Riociguat represents a novel therapeutic option for managing pulmonary hypertension through dual NO-independent and NO-dependent mechanisms. Buy high quality Riociguat from Omsynth Lifesciences.