IMPURITIES AVAILABLE FOR 'Palonosetron'

Omsynth Lifesciences Pvt. Ltd. is one of the leading manufacturer and exporter of Palonosetron. Palonosetron is a selective serotonin (5-HT₃) receptor antagonist used for the prevention of nausea and vomiting associated with chemotherapy, radiotherapy, and surgery. It works by blocking 5-HT₃ receptors both centrally in the chemoreceptor trigger zone and peripherally in the gastrointestinal tract, thereby inhibiting the emetic reflex. Palonosetron has a high receptor binding affinity and an exceptionally long half-life (around 40 hours), allowing for prolonged antiemetic protection with a single dose. It can be administered intravenously or orally prior to chemotherapy. The drug is metabolized in the liver (mainly via CYP2D6) and excreted in urine. Common side effects include headache, constipation, and dizziness. Compared to first-generation 5-HT₃ antagonists, palonosetron offers superior efficacy and duration, especially for delayed chemotherapy-induced nausea and vomiting (CINV). Buy high quality Palonosetron from Omsynth Lifesciences.