IMPURITIES AVAILABLE FOR 'Entacapone'

Omsynth Lifesciences Pvt. Ltd. is one of the leading manufacturer and exporter of Entacapone. Entacapone is a reversible inhibitor of catechol-O-methyltransferase (COMT), an enzyme that degrades Levodopa. It is used as an add-on medication in the treatment of Parkinson’s disease alongside Levodopa and Carbidopa. Entacapone prolongs the effects of Levodopa by inhibiting its peripheral breakdown, thereby increasing its availability in the brain. It predominantly inhibits peripheral COMT without crossing the blood-brain barrier. Side effects may include diarrhea, urine discoloration (orange or brown), and an increase in Levodopa-related effects such as dyskinesias and nausea. It is typically taken with each Levodopa dose during the day. Entacapone is well absorbed from the gastrointestinal tract and mainly eliminated through glucuronidation and excretion in the bile. Buy high quality Entacapone from Omsynth Lifesciences.