IMPURITIES AVAILABLE FOR 'Dacomitinib'

Omsynth Lifesciences Pvt. Ltd. is one of the leading manufacturer and exporter of Dacomitinib. Dacomitinib is an oral, irreversible tyrosine kinase inhibitor (TKI) that targets the epidermal growth factor receptor (EGFR) family, including EGFR/HER1, HER2, and HER4. It is primarily used to treat metastatic non-small cell lung cancer (NSCLC) in patients with EGFR-activating mutations. By blocking EGFR signaling pathways, dacomitinib inhibits cancer cell proliferation and survival. It is particularly effective in patients with exon 19 deletions or exon 21 (L858R) substitution mutations. Common side effects include diarrhea, rash, stomatitis, dry skin, and decreased appetite. Serious adverse effects may include interstitial lung disease and liver enzyme elevations. Due to its long half-life, dacomitinib is taken once daily, and dose adjustments may be required for toxicity. Liver function and dermatologic health should be monitored during treatment. Buy high quality Dacomitinib from Omsynth Lifesciences.