IMPURITIES AVAILABLE FOR 'Cilastatin Sodium'

Omsynth Lifesciences Pvt. Ltd. is one of the leading manufacturer and exporter of Cilastatin Sodium. Cilastatin Sodium is a renal dehydropeptidase-I (DHP-I) inhibitor used in combination with imipenem, a broad-spectrum carbapenem antibiotic. It works by preventing the degradation of imipenem in the kidneys, thereby increasing its urinary concentration and effectiveness. Cilastatin itself has no antibacterial activity but plays a crucial role in preserving imipenem's efficacy and reducing its potential nephrotoxicity. This combination is used to treat a wide range of serious bacterial infections, including those caused by multidrug-resistant organisms. Cilastatin is administered intravenously along with imipenem. Common side effects may include nausea, vomiting, diarrhea, and skin rash. Serious but rare adverse effects can include seizures, especially in patients with CNS disorders or renal impairment. Dose adjustment is required in patients with kidney dysfunction, and monitoring of renal function is essential during therapy. Buy high quality Cilastatin Sodium from Omsynth Lifesciences.