IMPURITIES AVAILABLE FOR 'Amonafide'

Omsynth Lifesciences Pvt. Ltd. is one of the leading manufacturer and exporter of Amonafide. Amonafide is an investigational anticancer agent belonging to the class of DNA intercalating agents with topoisomerase II inhibitory activity. It is primarily studied for the treatment of various malignancies, including acute myeloid leukemia (AML) and solid tumors such as breast and lung cancer. Amonafide works by inserting itself between DNA base pairs, disrupting DNA replication and transcription, and inducing cell cycle arrest and apoptosis in rapidly dividing cancer cells. Unlike traditional topoisomerase inhibitors, it has a distinct mechanism with reduced cross-resistance. It is typically administered intravenously. Side effects reported in clinical trials include myelosuppression, nausea, vomiting, and liver enzyme elevation. Its development has faced challenges due to variable drug metabolism among patients. Further studies are ongoing to optimize its therapeutic use. Buy high quality Amonafide from Omsynth Lifesciences.