IMPURITIES AVAILABLE FOR 'Ambrisentan'

Omsynth Lifesciences Pvt. Ltd. is one of the leading manufacturer and exporter of Ambrisentan. Ambrisentan is an endothelin receptor antagonist (ERA) primarily used for the treatment of pulmonary arterial hypertension (PAH) to improve exercise capacity and delay disease progression. It works by selectively blocking the endothelin type-A (ETA) receptors on vascular smooth muscle cells, leading to vasodilation and reduced pulmonary arterial pressure. Unlike some other ERAs, ambrisentan has higher selectivity for ETA receptors, which may reduce side effects related to endothelin type-B (ETB) blockade. It is usually administered orally once daily and may be used alone or in combination with other PAH therapies. Common side effects include peripheral edema, headache, nasal congestion, flushing, and palpitations. Due to its potential hepatotoxicity and teratogenic effects, regular liver function tests and pregnancy monitoring are recommended. Ambrisentan offers a well-tolerated and effective option for long-term PAH management. Buy high quality Ambrisentan from Omsynth Lifesciences.